From City of Buffalo: 

• Route 33 East
• Harlem Road Exit toward Pine Ridge Road
• Continue on Maryvale Dr.
• Left onto Harlem Road (Route 240S)

From Southtowns

• I-90 East
• Exit 50A towards Cleveland Drive
• Left onto Cleveland Drive (CR-141)
• Right onto Harlem Road (Route 240N)

From Amherst and Tonawanda

• I-290 East
• Exit #6 Sheridan Drive/Harlem Road
• Left onto Harlem Road (Route 240S)

From Lancaster and Depew

• Transit Road North
• Left onto Wehrle Drive
• Right on Harlem Road (Route 240N)